Depression

Depression is a passive item added in Afterbirth †.

Effect

 * Spawns a rain cloud familiar that follows Isaac and leaves behind a trail of damaging blue creep.
 * The creep deals 2 damage per tick or 6 damage per second to non-flying enemies.
 * If the cloud touches an enemy, it has a small chance to spawn a damaging Holy Light beam onto the enemy.
 * The light beams deal 20 + Isaac's base damage per tick and may strike an enemy up to 8 times.
 * The creep will not deal damage to Isaac.

Interactions

 * : Increase cloud size but does not increase damage.
 * : Cloud will remain in place relative to Isaac.
 * : Cloud will occasionally connected to Isaac via electricity.
 * : Increases size of creep trail.

Trivia

 * This item is a reference to real life depression which is a time of sadness, hopelessness, or worthlessness that lasts at least two weeks, hence the pick-up quote being a sad face.

Seeds
VZ7K 0GXN (Adjacent to spawn) (Normal mode only)